Ibrance MOA, Dosage, Cost, Generic, Side Effects, Survival Rate

 Ibrance FAQ: Is It Right for You?

What is Ibrance?It's a prescription medication used to treat a type of advanced breast cancer in adults.
What's Ibrance (MOA) Mechanism of Action?As a cyclic dependent kinases 4 & 6 inhibitor, it targets the CDK4/6 pathway and stops the growth of the tumor cells and the growth of the tumor itself.
Ibrance DosageThe recommended dose is 125 mg once daily for 21 consecutive days, then one week break.
Cost / Price of IbranceThe cost for a supply of 21 capsules is about $13,000.
Ibrance GenericIts generic name is palbociclib.
Ibrance Side Effects
Side effects include the following:

• nausea
• vomiting
• reduced or loss of appetite
• diarrhea
• exhaustion
• weakness
• hair loss
• mouth sores
• numbness/tingling of legs/arms
• low white blood cell count

Ibrance Survival Rate

Median overall survival was 34.9 months for female patients receiving Ibrance treatment with Faslodex.

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Imbruvica MOA, Dosage, Cost, Generic, Side Effects, Survival Rate

 Imbruvica FAQ: Is It Right for You?

What is Imbruvica?

It's a cancer drug used to treat mantle cell lymphoma, chronic lymphocytic leukemia, or marginal zone lymphoma.

What's Imbruvica (MOA) Mechanism of Action?

Since this drug blocks BTK signaling, it helps stop B cells from surviving and multiplying. Essentially, the drug interferes with the development and spread of cancer cells in your body.

Imbruvica Dosage

The recommended dose is typically a low one, or 70 mg. Your doctor will start you on a low dose before adjusting it over time to reach the higher 140 mg dose.

Cost / Price of Imbruvica

The cost for a supply of 28 Imbruvica capsules is about $11,877.

Imbruvica Generic

Its generic name is ibrutinib.

Imbruvica Side Effects

Common side effects include the following:

• muscle spasms
• diarrhea
• exhaustion
• low platelet count
• neutropenia
• anemia
• musculoskeletal pain
• infection
• bruise
• cytopenia
• thrombocytopenia

Imbruvica Survival Rate

Data demonstrate 59% progression free survival and 74% overall survival in CLL/SLL patients treated with Imbruvica.

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Rituxan MOA, Dosage, Cost, Generic, Side Effects, Survival Rate

 Rituxan FAQ: Is It Right for You?

What is Rituxan?

It's a prescription drug used to treat specific kinds of cancer like chronic lymphocytic leukemia and non-Hodgkin's lymphoma.

What is Rituxan (MOA) Mechanism of Action?

It works in various ways to locate and then destroy the cells where cancer begins.

Rituxan Dosage

The recommended dosage is 375 mg day before the start of FC chemotherapy, then 500 mg on Day 1 of cycles 2 to 6 every 28 days.

Cost / Price of Rituxan

The cost is about $999 for a supply of 10 milliliters. Medicare prescription drug plans do not cover this medication.

Rituxan Generic

Its generic name is Rituximab.

Rituxan Side Effects

Potential side effects include the following:

• cuts, scrapes or incisions which are warm, swollen or painful
• pain during urination
• cold sores in throat or mouth
• fever
• earache or headache
• flu symptoms

Rituxan Survival Rate

After a median follow-up of 79.9 months, the 5-year cancer-free survival rate was 79% with Rituxan maintenance, according to one source. However, according to Biomedcentral, there were 11 deaths after Rituxan treatment.

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