Venclexta MOA, Dosage, Cost, Generic, Side effects, Survival Rate

 Venclexta FAQ: Is It Right for You?

What is Venclexta?

It's a medication used to treat cancers such as acute myeloid leukemia, small lymphocytic lymphoma, and chronic lymphocytic leukemia.

What's Venclexta (MOA) Mechanism of Action?

It works by blocking the anti-apoptotic B-cell lymphoma-2 protein, which leads to programmed cell death of CLL cells.

Venclexta Dosage

Its starting dose is 20 mg once daily for a week. Then goes up to 50 mg the second week, 100 mg the next, 200 mg, and eventually to 400 mg once daily.

Cost / Price of Venclexta

The cost is about $128 for only one single tablet, without health insurance.

Venclexta Generic

Its generic name is venetoclax.

Venclexta Side Effects

Reported side effects include:

• nausea
• vomiting
• diarrhea or constipation
• exhaustion
• stomach ache
• fluid buildup in your body
• muscle or joint pain
• fever
• irritability
• restlessness
• seizures
• confusion
• chills
• irregular heartbeat
• dark or cloudy urine
• rash
• cough
• anemia
• low white blood cell count

Venclexta Survival Rate

In a study, 36.7% of patients in the Venclexta group saw complete remission.

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Jakafi MOA, Dosage, Cost, Generic, Side Effects, Survival Rate

 Jakafi FAQ: Is It Right for You?

What is Jakafi?

It's a prescription medicine used to treat cancers like polycythemia vera and myelofibrosis.

What's Jakafi (MOA) Mechanism of Action?

The medication stops the growth of cancerous cells and regulates cytokines which contribute to hypermetabolic state.

Jakafi Dosage

The recommended dose is 5 mg administered orally twice a day.

Cost / Price of Jakafi

Without health insurance, expect to pay around $14,821 for a supply of 60 5 mg tablets.

Jakafi Generic

It's generic name is ruxolitinib.

Jakafi Side Effects

Common side effects include:

• gas
• low blood platelet levels
• bloating
• weight gain
• urinary tract infections
• headache
• dizziness
• bruising
• black stools
• bladder pain
• bleeding gums
• bloody urine
• blurred vision
• chest tightness
• anemia
• balance impairment 

Jakafi Survival Rate

Median overall survival time frame was 5.3 years when treated with Jakafi.

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Xtandi MOA, Dosage, Cost, Generic, Side Effects, Survival Rate

 Xtandi FAQ: Is It Right For You?

What is Xtandi?

It's a prescription drug used to treat prostate cancer, which doesn't respond any longer to other treatments.

What's Xtandi (MOA) Mechanism of Action?

It prevents the translocation of the AR from the cytoplasm to the nucleus. Inside the nucleus, it inhibits AR binding to chromosomal DNA, which prevents additional transcription of tumor genes.

Xtandi Dosage

Recommended dose is 160 mg given orally only once a day.

Cost / Price of Xtandi

A supply of 120 capsules at 40 mg of Xtandi costs about $13,698.

Xtandi Generic

Its generic name is enzalutamide.

Xtandi Side Effects

Common side effects include:

• headache
• high blood pressure
• dizziness
• joint pain
• hot flashes
• reduced appetite
• weakness
• exhaustion
• constipation
• back pain
• diarrhea
• bloody urine
• muscle pain

Xtandi Survival Rate

In a study, the Xtandi group saw a 70.6% survival rate by the fourth year.

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