Xtandi MOA, Dosage, Cost, Generic, Side Effects, Survival Rate

 Xtandi FAQ: Is It Right For You?

What is Xtandi?

It's a prescription drug used to treat prostate cancer, which doesn't respond any longer to other treatments.

What's Xtandi (MOA) Mechanism of Action?

It prevents the translocation of the AR from the cytoplasm to the nucleus. Inside the nucleus, it inhibits AR binding to chromosomal DNA, which prevents additional transcription of tumor genes.

Xtandi Dosage

Recommended dose is 160 mg given orally only once a day.

Cost / Price of Xtandi

A supply of 120 capsules at 40 mg of Xtandi costs about $13,698.

Xtandi Generic

Its generic name is enzalutamide.

Xtandi Side Effects

Common side effects include:

• headache
• high blood pressure
• dizziness
• joint pain
• hot flashes
• reduced appetite
• weakness
• exhaustion
• constipation
• back pain
• diarrhea
• bloody urine
• muscle pain

Xtandi Survival Rate

In a study, the Xtandi group saw a 70.6% survival rate by the fourth year.

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Perjeta MOA, Dosage, Cost, Generic, Side Effects, Survival Rate

 Perjeta FAQ: It Is Right for You?

What is Perjeta?

It's a chemotherapy drug used to treat breast cancer.

What's Perjeta (MOA) Mechanism of Action?

It binds to an extracellular domain of the receptor 2, stops HER2 homodimerization, and then prevents HER2-mediated signaling.

Perjeta Dosage

Its first dose is 840 mg given as a 60-minute intravenous infusion, followed every 3 weeks by a dosage of 420 mg.

Cost / Price of Perjeta

Without health insurance, it costs about $6,217 for a supply of 14 milliliters.

Perjeta Generic

Its generic name is pertuzumab.

Perjeta Side Effects

Potential side effects include:

• peripheral neuropathy
• rash
• exhaustion
• low white blood cell count
• hair loss
• diarrhea
• reduced appetite
• muscle sores
• weakness
• anemia
• swelling
• muscle aches
• nail changes
• joint aches
• vomiting
• nausea
• numbness
• headaches
• risk of infection

Perjeta Survival Rate

Patients saw 32% reduction in the danger of death.

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Darzalex MOA, Dosage, Cost, Generic, Side Effects, Survival Rate

 Darzalex FAQ: Is It Right for You?

What is Darzalex?

It's a prescription drug often used to treat multiple myeloma.

What's Darzalex (MOA) Mechanism of Action?

It works by either directly destroying multiple myeloma cells or allowing the immune system to identify and kill them.

Darzalex Dosage

Recommended dose is 16 milligrams/kilograms of actual body weight as an IV infusion.

Cost / Price of Darzalex

It costs about $656 for a supply of 5 milliliters.

Darzalex Generic

Its generic name is daratumumab.

Darzalex Side Effects

The most common side effects include:

• cold-like symptoms
• pain or numbness
• nerve damage that causes tingling
• swollen hands, ankles or feet
• shortness of breath
• cough
• trouble sleeping
• dizziness
• chills 
• fever
• back pain
• joint pain
• muscle spasms
• vomiting
• constipation
• diarrhea
• nausea
• exhaustion

Darzalex Survival Rate

Median overall survival time was 20.1 months.

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Tecentriq MOA, Dosage, Cost, Generic, Side Effects, Survival Rate

 Tecentriq FAQ: Is It Right for You?

What is Tecentriq?

It's a prescription drug used to treat a bladder and urinary tract cancer known as urothelial carcinoma and lung cancer.

What's Tecentriq (MOA) Mechanism of Action?

It works by blocking antibody and targeting the ligand PD-L1 to restore antitumor t-cell activity.

Tecentriq Dosage

The recommended dose is 1200 mg as an intravenous infusion every 4 weeks until free of cancer or treatments becomes too toxic.

Cost / Price of Tecentriq

It costs about $13,860 monthly.

Tecentriq Generic

Its generic name is atezolizumab.

Tecentriq Side Effects

Possible side effects include:

• constipation
• fever
• cough
• weakness
• fatigue
• reduced appetite
• diarrhea
• reduced levels of hemoglobin
• leukopenia
• nausea
• vomiting
• stomach pain
• urinary tract infection
• bloating
• bloody or cloudy urine
• blurred vision
• high blood pressure

Tecentriq Survival Rate

12-month overall survival rate was 66.1%.

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Doxil MOA, Dosage, Cost, Generic, Side Effects, Survival Rate

 Doxil FAQ: Is It Right for You?

What is Doxil?

It's a cancer drug used to treat metastatic ovarian cancer, breast cancer, and other solid tumors.

What's Doxil (MOA) Mechanism of Action?

By blocking the enzyme topo isomerase 2, it either slows or stops the growth of cancer cells.

Doxil Dosage

The recommended dose for Doxil is 50 mg/ml intravenously over 60 minutes each 28 days till the disease improves or the treatment becomes too toxic.

Cost / Price of Doxil

Without health insurance, the cost is about $708 for a supply of 10 milliliters. 

Doxil Generic

Its generic name is Doxorubicin Liposomal.

Doxil Side Effects

Potential side effects include:

• body pain
• headache
• nausea
• vomiting
• constipation
• diarrhea
• stomach upset
• loss of appetite
• hair loss
• weakness
• low energy level
• sore throat
• fever
• tingling
• numbness

Doxil Survival Rate

Overall median survival was 14.4 months.

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Daunorubicin MOA, Dosage, Cost, Generic, Side Effects, Survival Rate

 Daunorubicin FAQ: Is It Right for You?

What is Daunorubicin?

It's a chemotherapy medication used to treat cancer like acute myeloid leukaemia and acute lymphoblastic leukaemia.

What's Daunorubicin (MOA) Mechanism of Action?

It works by either doing one of two things, slowing or stopping the growth of cancer cells by blocking a necessary enzyme known as topo isomerase 2.

Daunorubicin Dosage

There exists a lifetime, or cumulative dose limitation, varying between 400 to 550 mg for adults. If you exceed these doses, the patient may experience a heart attack.

Cost / Price of Daunorubicin

Its intravenous solution costs about $146 for a supply of 4 milliliters.

Daunorubicin Generic

It's the generic name for the trade name drug Cerubidine.

Daunorubicin Side Effects

Potential side effects include the following:

• higher danger of infection
• breathlessness
• bruising
• nosebleeds or bleeding gums
• allergic reaction
• uncommon exhaustion
• fast weight gain
• dry mouth
• trouble swallowing or talking
• swelling in ankles or feet
• red urine

Daunorubicin Survival Rate

Overall survival rate 5-year after diagnosis was 23% and 19% after 10 years.

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Cytoxan MOA, Dosage, Cost, Generic, Side Effects, Survival Rate

Cytoxan FAQ: Is It Right for You?

What is Cytoxan?

It's a chemotherapy drug, classified as a "cytotoxic agent" since it causes a toxic effect on both good and bad cells. The medication is used to treat many types of cancer.

What's Cytoxan (MOA) Mechanism of Action?

It works by destroying cells which are about to divide into two new cells.

Cytoxan Dosage

The typical dose is between 1 to 5 milligrams per kilogram of body weight. Your doctor will determine the right dose for you.

Cost / Price of Cytoxan

The cost is about $231 for a supply of 1 gram powder for injection.

Cytoxan Generic

Its generic name is cyclophosphamide.

Cytoxan Side Effects

The common side effects include the following:

• nausea
• vomiting
• loss of appetite
• stomach upset or pain
• diarrhea
• temporary hair loss
• missed menstrual periods
• changes in skin color

Cytoxan Survival Rate

Overall cancer-free survival at 5 years after treatment were 62.6% and 64.3%.

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