Doxorubicin MOA, Dosage, Cost, Generic, Side Effects, Survival Rate

 Doxorubicin FAQ: Is It Right for You?

What is Doxorubicin?

It's a chemotherapy drug used to treat cancer.

What's Doxorubicin (MOA) Mechanism of Action?

It works by first blocking the enzyme topo isomerase 2 before slowing or stopping the growth of cancer.

Doxorubicin Dosage

35 to 7mg/m2 intravenously each 21 days; or 20 to 30 mg/m2 dose once a week

Cost / Price of Doxorubicin

The cost is about $16 for a supply of 5 milliliters of Doxorubicin.

Doxorubicin Generic

Its the generic name for the trade name drug, Adriamycin.

Doxorubicin Side Effects

Potential side effects include:

• cough
• darkening of skin
• rapid or irregular heartbeat
• fever or chills
• joint pain
• side or lower back pain followed by chills or fever
• pain at the injection area
• nausea
• vomiting
• sores in the mouth or throat
• loss of appetite
• stomach pain
• diarrhea
• increased thirst

Doxorubicin Survival Rate

The 5-year survival rate is estimated to be 50%.

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Venclexta MOA, Dosage, Cost, Generic, Side effects, Survival Rate

 Venclexta FAQ: Is It Right for You?

What is Venclexta?

It's a medication used to treat cancers such as acute myeloid leukemia, small lymphocytic lymphoma, and chronic lymphocytic leukemia.

What's Venclexta (MOA) Mechanism of Action?

It works by blocking the anti-apoptotic B-cell lymphoma-2 protein, which leads to programmed cell death of CLL cells.

Venclexta Dosage

Its starting dose is 20 mg once daily for a week. Then goes up to 50 mg the second week, 100 mg the next, 200 mg, and eventually to 400 mg once daily.

Cost / Price of Venclexta

The cost is about $128 for only one single tablet, without health insurance.

Venclexta Generic

Its generic name is venetoclax.

Venclexta Side Effects

Reported side effects include:

• nausea
• vomiting
• diarrhea or constipation
• exhaustion
• stomach ache
• fluid buildup in your body
• muscle or joint pain
• fever
• irritability
• restlessness
• seizures
• confusion
• chills
• irregular heartbeat
• dark or cloudy urine
• rash
• cough
• anemia
• low white blood cell count

Venclexta Survival Rate

In a study, 36.7% of patients in the Venclexta group saw complete remission.

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Jakafi MOA, Dosage, Cost, Generic, Side Effects, Survival Rate

 Jakafi FAQ: Is It Right for You?

What is Jakafi?

It's a prescription medicine used to treat cancers like polycythemia vera and myelofibrosis.

What's Jakafi (MOA) Mechanism of Action?

The medication stops the growth of cancerous cells and regulates cytokines which contribute to hypermetabolic state.

Jakafi Dosage

The recommended dose is 5 mg administered orally twice a day.

Cost / Price of Jakafi

Without health insurance, expect to pay around $14,821 for a supply of 60 5 mg tablets.

Jakafi Generic

It's generic name is ruxolitinib.

Jakafi Side Effects

Common side effects include:

• gas
• low blood platelet levels
• bloating
• weight gain
• urinary tract infections
• headache
• dizziness
• bruising
• black stools
• bladder pain
• bleeding gums
• bloody urine
• blurred vision
• chest tightness
• anemia
• balance impairment 

Jakafi Survival Rate

Median overall survival time frame was 5.3 years when treated with Jakafi.

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Xtandi MOA, Dosage, Cost, Generic, Side Effects, Survival Rate

 Xtandi FAQ: Is It Right For You?

What is Xtandi?

It's a prescription drug used to treat prostate cancer, which doesn't respond any longer to other treatments.

What's Xtandi (MOA) Mechanism of Action?

It prevents the translocation of the AR from the cytoplasm to the nucleus. Inside the nucleus, it inhibits AR binding to chromosomal DNA, which prevents additional transcription of tumor genes.

Xtandi Dosage

Recommended dose is 160 mg given orally only once a day.

Cost / Price of Xtandi

A supply of 120 capsules at 40 mg of Xtandi costs about $13,698.

Xtandi Generic

Its generic name is enzalutamide.

Xtandi Side Effects

Common side effects include:

• headache
• high blood pressure
• dizziness
• joint pain
• hot flashes
• reduced appetite
• weakness
• exhaustion
• constipation
• back pain
• diarrhea
• bloody urine
• muscle pain

Xtandi Survival Rate

In a study, the Xtandi group saw a 70.6% survival rate by the fourth year.

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Perjeta MOA, Dosage, Cost, Generic, Side Effects, Survival Rate

 Perjeta FAQ: It Is Right for You?

What is Perjeta?

It's a chemotherapy drug used to treat breast cancer.

What's Perjeta (MOA) Mechanism of Action?

It binds to an extracellular domain of the receptor 2, stops HER2 homodimerization, and then prevents HER2-mediated signaling.

Perjeta Dosage

Its first dose is 840 mg given as a 60-minute intravenous infusion, followed every 3 weeks by a dosage of 420 mg.

Cost / Price of Perjeta

Without health insurance, it costs about $6,217 for a supply of 14 milliliters.

Perjeta Generic

Its generic name is pertuzumab.

Perjeta Side Effects

Potential side effects include:

• peripheral neuropathy
• rash
• exhaustion
• low white blood cell count
• hair loss
• diarrhea
• reduced appetite
• muscle sores
• weakness
• anemia
• swelling
• muscle aches
• nail changes
• joint aches
• vomiting
• nausea
• numbness
• headaches
• risk of infection

Perjeta Survival Rate

Patients saw 32% reduction in the danger of death.

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Darzalex MOA, Dosage, Cost, Generic, Side Effects, Survival Rate

 Darzalex FAQ: Is It Right for You?

What is Darzalex?

It's a prescription drug often used to treat multiple myeloma.

What's Darzalex (MOA) Mechanism of Action?

It works by either directly destroying multiple myeloma cells or allowing the immune system to identify and kill them.

Darzalex Dosage

Recommended dose is 16 milligrams/kilograms of actual body weight as an IV infusion.

Cost / Price of Darzalex

It costs about $656 for a supply of 5 milliliters.

Darzalex Generic

Its generic name is daratumumab.

Darzalex Side Effects

The most common side effects include:

• cold-like symptoms
• pain or numbness
• nerve damage that causes tingling
• swollen hands, ankles or feet
• shortness of breath
• cough
• trouble sleeping
• dizziness
• chills 
• fever
• back pain
• joint pain
• muscle spasms
• vomiting
• constipation
• diarrhea
• nausea
• exhaustion

Darzalex Survival Rate

Median overall survival time was 20.1 months.

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Tecentriq MOA, Dosage, Cost, Generic, Side Effects, Survival Rate

 Tecentriq FAQ: Is It Right for You?

What is Tecentriq?

It's a prescription drug used to treat a bladder and urinary tract cancer known as urothelial carcinoma and lung cancer.

What's Tecentriq (MOA) Mechanism of Action?

It works by blocking antibody and targeting the ligand PD-L1 to restore antitumor t-cell activity.

Tecentriq Dosage

The recommended dose is 1200 mg as an intravenous infusion every 4 weeks until free of cancer or treatments becomes too toxic.

Cost / Price of Tecentriq

It costs about $13,860 monthly.

Tecentriq Generic

Its generic name is atezolizumab.

Tecentriq Side Effects

Possible side effects include:

• constipation
• fever
• cough
• weakness
• fatigue
• reduced appetite
• diarrhea
• reduced levels of hemoglobin
• leukopenia
• nausea
• vomiting
• stomach pain
• urinary tract infection
• bloating
• bloody or cloudy urine
• blurred vision
• high blood pressure

Tecentriq Survival Rate

12-month overall survival rate was 66.1%.

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