Nivolumab MOA, Dosage, Cost, Generic, Side Effects, Survival Rate

 Nivolumab FAQ: Is It Right for You?

What is Nivolumab?

It's a prescription drug used to treat cancer of the lining of the urinary tract.

What's Nivolumab (MOA) Mechanism of Action?

It works by preventing cancer cells from disguising themselves and permitting your T cells to become active and attack cancer cells once again.

Nivolumab Dosage

Dose varies from 2.5 mg to 10 mg daily orally or 20 to 300 mg daily orally divided every 6 to 8 hours.

Cost / Price of Nivolumab

Without health insurance, the cost for the Nivolumab-ipilimumab combo treatment is about $377,400.

Nivolumab Generic

It's the generic name for Opdivo, the trade drug name.

Nivolumab Side Effects

Common side effects include:

• increased AST
• low blood sodium level
• increased alkaline phosphatase
• rash
• terrible itching
• cough
• upper respiratory tract infection
• high blood potassium levels
• fatigue
• low white blood cell count
• shortness of breath
• musculoskeletal pain
• reduced appetite

Nivolumab Survival Rate

When treated with nivolumab and ipilimumab, patients saw a median survival of 72.1 months.

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Yervoy MOA, Dosage, Cost, Generic, Side effects, Survival Rate

 Yervoy FAQ: Is It Right for You?

What is Yervoy?

It's a prescription drug used to treat skin cancer symptoms, Renal cell carcinoma, Hepatocellular Carcinoma, and non-small cell lung cancer.

What's Yervoy (MOA) Mechanism of Action?

It works by helping to turn on the immune response, which allows T cells to start attacking cancer cells.

Yervoy Dosage

The recommended dose is 3 mg/kg given intravenously over 90 minutes each 3 weeks for no more than 4 doses.

Cost / Price of Yervoy

Without health insurance, it costs about $8,310 for a supply of 10 milliliters.

Yervoy Generic

Its generic name is ipilimumab.

Yervoy Side Effects

Most common side effects include:

• exhaustion
• diarrhea
• nausea
• itching
• rash
• vomiting
• headache
• weight loss
• fever
• reduced appetite
• falling or staying asleep difficulty

Yervoy Survival Rate

Together Yervoy and Opdivo resulted in a 75% survival rate at 18 months.

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Idarubicin MOA, Dosage, Cost, Generic, Side Effects, Survival Rate

 Idarubicin FAQ: Is It Right for You?

What is Idarubicin?

It's a chemotherapy medication used to treat certain cancers like AML and ALL.

What's Idarubicin (MOA) Mechanism of Action?

It works by inducing DNA strand breaks in leukemic cells, damaging them.

Idarubicin Dosage

As a single agent, the recommended dose is 12 mg/m2 intravenously daily for 3 days.

Cost / Price of Idarubicin

The cost is about $40 for a supply of 5 milliliters.

Idarubicin Generic

It's the generic name for the trade name drug, Idamycin PFS.

Idarubicin Side Effects

Potential side effects include:

• nausea
• vomiting
• diarrhea
• sores in the mouth and throat
• stomach pain
• headache
• joint pain
• hair loss
• fever
• nail thickening
• skin discoloration
• cracked lips

Idarubicin Survival Rate

Complete remission rate for all patients was 63.4%.

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Epirubicin MOA, Dosage, Cost, Generic, Side Effects, Survival Rate

 Epirubicin FAQ: Is It Right for You?

What is Epirubicin?

It's a chemotherapy drug used to treat several kinds of cancer.

What's Epirubicin (MOA) Mechanism of Action?

It works by first damaging the DNA in cancer cells, and then causing them to die.

Epirubicin Dosage

Recommended dose is 100 to 120 mg/m2 given intravenously over 15 to 20 minutes.

Cost / Price of Epirubicin

It costs about $59 for a supply of 25 milliliters.

Epirubicin Generic

It's the generic name for the trade name drug, Ellence.

Epirubicin Side Effects

• black, tarry stools
• chest pain
• bleeding, redness, or ulcers in throat or mouth
• cough or hoarseness
• fever or chills
• pain or burning in throat or mouth
• sores, ulcers, or white spots in the mouth or on the lips
• nausea
• vomiting
• stomach ache
• diarrhea
• loss of appetite or weight
• uncommon exhaustion or weakness
• hair loss

Epirubicin Survival Rate

After 45 separate doses, the median progression-free survival was 9 months.

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Doxorubicin MOA, Dosage, Cost, Generic, Side Effects, Survival Rate

 Doxorubicin FAQ: Is It Right for You?

What is Doxorubicin?

It's a chemotherapy drug used to treat cancer.

What's Doxorubicin (MOA) Mechanism of Action?

It works by first blocking the enzyme topo isomerase 2 before slowing or stopping the growth of cancer.

Doxorubicin Dosage

35 to 7mg/m2 intravenously each 21 days; or 20 to 30 mg/m2 dose once a week

Cost / Price of Doxorubicin

The cost is about $16 for a supply of 5 milliliters of Doxorubicin.

Doxorubicin Generic

Its the generic name for the trade name drug, Adriamycin.

Doxorubicin Side Effects

Potential side effects include:

• cough
• darkening of skin
• rapid or irregular heartbeat
• fever or chills
• joint pain
• side or lower back pain followed by chills or fever
• pain at the injection area
• nausea
• vomiting
• sores in the mouth or throat
• loss of appetite
• stomach pain
• diarrhea
• increased thirst

Doxorubicin Survival Rate

The 5-year survival rate is estimated to be 50%.

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Venclexta MOA, Dosage, Cost, Generic, Side effects, Survival Rate

 Venclexta FAQ: Is It Right for You?

What is Venclexta?

It's a medication used to treat cancers such as acute myeloid leukemia, small lymphocytic lymphoma, and chronic lymphocytic leukemia.

What's Venclexta (MOA) Mechanism of Action?

It works by blocking the anti-apoptotic B-cell lymphoma-2 protein, which leads to programmed cell death of CLL cells.

Venclexta Dosage

Its starting dose is 20 mg once daily for a week. Then goes up to 50 mg the second week, 100 mg the next, 200 mg, and eventually to 400 mg once daily.

Cost / Price of Venclexta

The cost is about $128 for only one single tablet, without health insurance.

Venclexta Generic

Its generic name is venetoclax.

Venclexta Side Effects

Reported side effects include:

• nausea
• vomiting
• diarrhea or constipation
• exhaustion
• stomach ache
• fluid buildup in your body
• muscle or joint pain
• fever
• irritability
• restlessness
• seizures
• confusion
• chills
• irregular heartbeat
• dark or cloudy urine
• rash
• cough
• anemia
• low white blood cell count

Venclexta Survival Rate

In a study, 36.7% of patients in the Venclexta group saw complete remission.

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Jakafi MOA, Dosage, Cost, Generic, Side Effects, Survival Rate

 Jakafi FAQ: Is It Right for You?

What is Jakafi?

It's a prescription medicine used to treat cancers like polycythemia vera and myelofibrosis.

What's Jakafi (MOA) Mechanism of Action?

The medication stops the growth of cancerous cells and regulates cytokines which contribute to hypermetabolic state.

Jakafi Dosage

The recommended dose is 5 mg administered orally twice a day.

Cost / Price of Jakafi

Without health insurance, expect to pay around $14,821 for a supply of 60 5 mg tablets.

Jakafi Generic

It's generic name is ruxolitinib.

Jakafi Side Effects

Common side effects include:

• gas
• low blood platelet levels
• bloating
• weight gain
• urinary tract infections
• headache
• dizziness
• bruising
• black stools
• bladder pain
• bleeding gums
• bloody urine
• blurred vision
• chest tightness
• anemia
• balance impairment 

Jakafi Survival Rate

Median overall survival time frame was 5.3 years when treated with Jakafi.

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