Ibrance MOA, Dosage, Cost, Generic, Side Effects, Survival Rate

 Ibrance FAQ: Is It Right for You?

What is Ibrance?It's a prescription medication used to treat a type of advanced breast cancer in adults.
What's Ibrance (MOA) Mechanism of Action?As a cyclic dependent kinases 4 & 6 inhibitor, it targets the CDK4/6 pathway and stops the growth of the tumor cells and the growth of the tumor itself.
Ibrance DosageThe recommended dose is 125 mg once daily for 21 consecutive days, then one week break.
Cost / Price of IbranceThe cost for a supply of 21 capsules is about $13,000.
Ibrance GenericIts generic name is palbociclib.
Ibrance Side Effects
Side effects include the following:

• nausea
• vomiting
• reduced or loss of appetite
• diarrhea
• exhaustion
• weakness
• hair loss
• mouth sores
• numbness/tingling of legs/arms
• low white blood cell count

Ibrance Survival Rate

Median overall survival was 34.9 months for female patients receiving Ibrance treatment with Faslodex.

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Imbruvica MOA, Dosage, Cost, Generic, Side Effects, Survival Rate

 Imbruvica FAQ: Is It Right for You?

What is Imbruvica?

It's a cancer drug used to treat mantle cell lymphoma, chronic lymphocytic leukemia, or marginal zone lymphoma.

What's Imbruvica (MOA) Mechanism of Action?

Since this drug blocks BTK signaling, it helps stop B cells from surviving and multiplying. Essentially, the drug interferes with the development and spread of cancer cells in your body.

Imbruvica Dosage

The recommended dose is typically a low one, or 70 mg. Your doctor will start you on a low dose before adjusting it over time to reach the higher 140 mg dose.

Cost / Price of Imbruvica

The cost for a supply of 28 Imbruvica capsules is about $11,877.

Imbruvica Generic

Its generic name is ibrutinib.

Imbruvica Side Effects

Common side effects include the following:

• muscle spasms
• diarrhea
• exhaustion
• low platelet count
• neutropenia
• anemia
• musculoskeletal pain
• infection
• bruise
• cytopenia
• thrombocytopenia

Imbruvica Survival Rate

Data demonstrate 59% progression free survival and 74% overall survival in CLL/SLL patients treated with Imbruvica.

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Rituxan MOA, Dosage, Cost, Generic, Side Effects, Survival Rate

 Rituxan FAQ: Is It Right for You?

What is Rituxan?

It's a prescription drug used to treat specific kinds of cancer like chronic lymphocytic leukemia and non-Hodgkin's lymphoma.

What is Rituxan (MOA) Mechanism of Action?

It works in various ways to locate and then destroy the cells where cancer begins.

Rituxan Dosage

The recommended dosage is 375 mg day before the start of FC chemotherapy, then 500 mg on Day 1 of cycles 2 to 6 every 28 days.

Cost / Price of Rituxan

The cost is about $999 for a supply of 10 milliliters. Medicare prescription drug plans do not cover this medication.

Rituxan Generic

Its generic name is Rituximab.

Rituxan Side Effects

Potential side effects include the following:

• cuts, scrapes or incisions which are warm, swollen or painful
• pain during urination
• cold sores in throat or mouth
• fever
• earache or headache
• flu symptoms

Rituxan Survival Rate

After a median follow-up of 79.9 months, the 5-year cancer-free survival rate was 79% with Rituxan maintenance, according to one source. However, according to Biomedcentral, there were 11 deaths after Rituxan treatment.

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Avastin MOA, Dosage, Cost, Generic, Side Effects, Survival Rate

 Avastin FAQ: Is It Right for You?

What is Avastin?

It's a cancer drug used to treat several different kinds of cancer such as lung, colorectal, kidney, cervical, glioblastoma, and ovarian cancer.

What is Avastin (MOA) Mechanism of Action?

It works by first binding and then preventing the action of VEGF with its interaction with its receptors on endothelial cells.

Avastin Dosage

The recommended dosage is 15 mg intravenously every 3 weeks in combination with carboplatin and paclitaxel for up to 6 cycles.

Cost / Price of Avastin

Avastin costs about $849 for a supply of 4 milliliters, depending on the pharmacy you visit.

Avastin Generic

Its generic name is bevacizumab.

Avastin Side effects

The common side effects include the following:

• weakness
• pain
• abdominal pain
• nausea & vomiting
• reduced appetite
• constipation
• upper respiratory infection
• low white blood cell count
• nosebleed
• diarrhea
• hair loss
• mouth sores
• headache
• proteinuria

Avastin Survival Rate

43% of patients saw six-month progression-free of cancer after receiving treatment with Avastin.

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Herceptin MOA, Dosage, Cost, Generic, Side effects, Survival Rate

Herceptin

Herceptin FAQ

What is Herceptin?

It's a medication used alone or with others to treat specific kinds of breast cancer, gastroesophageal junction cancer, and stomach cancer which are HER2 positive.

What is Herceptin (MOA) Mechanism of Action?

By weakening the signal transduction downstream, Herceptin might promote apoptosis and stop cell proliferation. In addition, it flags the tumor cell for destruction through your body's immunity.

Herceptin Dosage

The initial dose is 8 mg as a 90-minute intravenous infusion; then subsequent doses of 6 mg are given over 30 to 90 minutes every 3 weeks.

Cost / Price of Herceptin

A full year course costs around $70,000, or about $4,500 monthly. But many health insurance plans may cover most of the cost.

Herceptin Generic

Its generic trade name is Trastuzumab.

Herceptin Side Effects

The common side effects include the following:

• exhaustion
• joint pain
• diarrhea
• injection site reaction
• upper respiratory tract infection
• rash
• muscle pain
• nausea
• headache
• swelling
• flushing
• cough
• pain in extremity

Herceptin Survival Rate

After 10 years after treatment, women saw a better overall survival rate. 84% of the women who got chemotherapy and Herceptin were still alive.

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Keytruda MOA, Dosage, Cost, Generic, Side effects, Survival Rate

 Keytruda FAQ: Is It Right For You?

What is Keytruda?

It's a prescription medication used to treat advanced melanoma, non-small cell lung cancer, head and neck squamous cell carcinoma.

What is Keytruda (MOA) Mechanism of Action?

It works by modifying the action of your immunity, ordering it to attack cancer cells.

Keytruda Dosage

Take 20 mg once daily till disease improves, becomes intolerable, or too toxic, or up to 24 months.

Cost / Price of Keytruda

Keytruda costs around $12,500 per month. But most health insurance plans will cover 80% or more of the cost.

Keytruda Generic

Its generic name is pembrolizumab.

Keytruda Side Effects

Common side effects include the following:

• feeling tired
• muscular pain
• rash
• diarrhea
• fever
• cough
• reduced appetite
• itching
• shortness of breath
• constipation
• pain in bones, joints or stomach
• nausea
• low levels of thyroid hormone

Keytruda Survival Rate

The average overall survival duration among Keytruda treated patients is 26.3 months. Those who experienced a 36-month survival rate is 43.7%.

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Opdivo MOA, Dosage, Cost, Generic, Side Effects, Survival Rate

 Opdivo FAQ: Is It Right for You?

What is Opdivo?

It's a cancer drug used either alone or in combination with others to treat specific kinds of esophageal cancer, stomach cancer, gastroesophageal junction cancer, melanoma, non-small cell lung cancer, colorectal cancer, renal cell carcinoma, hepatocellular carcinoma.

What is Opdivo (MOA) Mechanism of Action?

Essentially, the drug works by changing the action of your immunity, instructing it to attack cancer cells.

Opdivo Dosage

The recommended dosage is 360 mg of Opdivo administered intravenously over 30 minutes each 3 weeks alone or in combination with cabozantinib.

Cost / Price of Opdivo

Depending on the exact dosage, Opdivo could cost $6,580 per infusion. But most health insurance companies pay a quarter of this cost.

Opdivo Generic

Its generic name is nivolumab.

Opdivo Side Effects

The most common side effects include the following:

• headache
• fever
• upper respiratory tract infection
• feeling exhausted
• rash
• back pain
• reduced appetite
• constipation
• cough
• shortness of breath
• vomiting
• nausea
• weakness
• itchy skin
• diarrhea
• pain in muscles, bones, or joints

What's Opdivo Survival Rate?

More than twice as many patients responded to Opdivo as opposed to Yervoy alone. Also, Opdivo was shown to either partly or fully reduce tumors in 19% of patients.

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